Clopidogrel

Analogs

Aterocard, Zylt, Clopidogrel – Ratiopharm, Lopigrol, Lopirel, Medogrel, Platogril, Atrogrel, Deplat, Cardogrel, Clopidogrel – Apotex, Clopidogrel – Pharmex, Pingel neo, Plavix, Plagril, Reodar, Tessiron, Tessiron, Trombonetrombex , Clopidogrel – Zentiva, Clopidogrel – Teva, Clodia, Nugrel, Oneclapz, Plazet, Arepleks.

pharmachologic effect

It has an anticoagulant effect.

Indications for use

Prevention of ischemic disorders in atherosclerotic vascular lesions.

Method of administration and dosage

Inside, 1 tablet (75 mg) 1 time per day, regardless of food intake. Treatment should begin within a period of several days to 35 days in patients after myocardial infarction and from 7 days to 6 months in patients after ischemic stroke. In patients with acute coronary syndrome without ST- segment elevation,   treatment with the drug should be started with a single dose of 300 mg on the first day of treatment, and then continued with a dose of 75 mg per day in combination with acetylsalicylic acid at a dose of 75–325 mg per day.     

Side effects

Hematuria, purple, nose, gastro – intestinal, conjunctival and intracranial hemorrhage; digestive disorders, abdominal pain, exacerbation of peptic ulcers of the stomach and duodenum; disorders of the liver, biliary tract; headache, dizziness; skin rash.

Contraindications

Hypersensitivity to the drug, pregnancy and lactation; childhood.

Overdose

Symptoms   Increased bleeding time.

Treatment.   Platelet transfusion.

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