Analogs
Nazin, Naphthyzin, Sanorin – analergin.
pharmachologic effect
When applied to the mucous membrane of the nasal cavity reduces its swelling, reduces blood flow to the venous sinuses, facilitates nasal breathing.
Indications for use
Acute and allergic rhinitis, acute sinusitis, acute otitis media, eustachitis, nosebleeds, rhinoscopy or surgical procedures in the nasal cavity. To slow the absorption of local anesthetics.
Dosage and administration
Nasal drops 0.05 % and 0.1 %, an emulsion for nasal application of 0.1 %: adults 1-3 drops of 0.1 % p – pa or emulsion into each nasal passage; for children aged 2–6 years, 1-2 drops of 0.05 % r – ra; 6-15 years – 2 drops of 0.05 % r – ra. Dosing regimen – 2-3 times a day with an interval of at least 4 hours.
Nasal spray 0.1 %: for adults and children over 15 years of age 1-3 spray irrigation in each nasal passage 3 times a day with an interval of at least 4 hours. One dose corresponds to 1 press on the bottle. Immediately after applying the spray, it is recommended to inhale through the nose.
For nosebleeds , swabs moistened with a 0.05 % solution are used. With rhinoscopy , 2–4 drops of 0.1 % r – ra with 1 ml of anesthetic.
The drug is not recommended for adults more than 1 week, children – more than 3 days.
Repeated use of the drug is possible only after a few days.
Side effects
Irritation of the mucous membrane, burning, dryness, reactive hyperemia, irritability, excessive sweating, weakness, tremor, nausea, headache, increased blood pressure, tachycardia.
Contraindications
Angle-closure glaucoma, intraocular hypertension, palpitations, hypertension, severe atherosclerosis, angina pectoris, diabetes mellitus, hyperthyroidism, inflammation of the nasal mucosa without secretion, increased individual sensitivity to the components of the drug, age up to 2 years, for 0.1 % p – pa – age up to 12 years.
When applying drops, emulsions: hypertension, tachycardia, severe atherosclerosis; enlargement of the thyroid gland, age up to 2 years.
When applying the spray: age up to 15 years, hypersensitivity to the drug, atrophic rhinitis.
Overdose
An overdose can cause nervousness, excessive sweating, headache, tremors, tachycardia, palpitations, hypertension, cyanosis, nausea, hyperthermia, cardiac arrest, pulmonary edema, mental disorders, bradycardia, drowsiness, hypotensive shock, apnea, and coma.
Treatment. Symptomatic