Analogs

Melaxen, Circadin.

Pharmacological action

A synthetic analog of the pineal gland hormone melatonin. The drug has antioxidant properties. Normalizes the permeability of the vascular wall and increases its resistance to damaging factors, improves microcirculation.

Indications for use

Sleep disorders, including in elderly patients; disruption of normal circadian rhythm as a result of rapid movement between time zones of the Earth, manifested by increased fatigue; depressive states that have a seasonal character.

Dosage and administration method

Inside from 3 to 6 mg (1-2 tablets) per day, 30 minutes before bedtime, preferably at the same time daily. The course of treatment is continued until the independent normal rhythm of sleep and wakefulness is restored.

Side effects

Headache, digestive disorders, skin rashes.

Contraindications

Allergic diseases, autoimmune diseases, lymphogranulomatosis, leukemia, lymphoma, myeloma, epilepsy, diabetes mellitus, pregnancy, breast-feeding, simultaneous treatment with MAO inhibitors, corticosteroids, cyclosporine.

Overdose

Symptoms. Cases of Vita‑melatonin overdose (simultaneous administration of 24-30 mg of the drug) are described. Overdose can lead to disorientation, prolonged sleep, and memory loss.

Treatment . Symptomatic.