Analogs

Antimigren – Health, Imigran , Migranol , Stopmigren , Sumamigren , Antimigren .

pharmachologic effect

It has a selective vasoconstrictor effect on the vessels of the carotid artery system, without affecting the cerebral blood flow. The expansion of these vessels is the main mechanism for the development of a migraine attack. The clinical effect develops within 30 minutes after taking the drug.

Indications for use

Relief of migraine attacks with or without aura.

Method of administration and dosage

Adults – 50 or 100 mg, depending on individual sensitivity. If symptoms recur, the dose can be added at intervals of at least 2 hours. The maximum daily dose is 200 mg. Antimigren is recommended to be used as early as possible when a migraine attack occurs, but it is equally effective at any stage of the attack.      

The drug should not be used prophylactically during the interictal period of migraine. The recommended daily dose for patients with hepatic impairment is 50 mg. 

Sumamigren can be prescribed for subsequent attacks. If the effect was noted after taking the first dose of the drug, but the migraine attack recurred, the drug can be used again over the next 24 hours, while the total daily dose should not exceed 300 mg. The tablets are swallowed whole with water.  

Side effects

Increase or decrease in blood pressure, fainting; sinusitis, ringing in the ears, rhinitis, inflammation of the upper respiratory tract, ear, nose and throat bleeding, otitis media, hearing impairment; heartburn, digestive disorders; muscle pain; light and sound fear ; shortness of breath, bronchospasm, sneezing; sweating; intermenstrual bleeding; chills, fever, fluid retention in the body.

Contraindications

Pathology cardio – vascular system; cerebral and peripheral circulation disorders, uncontrolled hypertension; severe liver failure; simultaneous administration of drugs containing ergotamine and its derivatives, MAO inhibitors, up to 14 days after their cancellation; period of pregnancy and lactation, age up to 14 years old and over 60 years old, hypersensitivity to the drug. The drug is not intended for the prevention of migraine attacks.

Overdose

Treatment.   Symptomatic.