Analogs

Beta – clatinol, Zolopent, Controlok, Nolpaza, Tecta control, Ulsepan, Panocid 40, Pantaz, Pantasan, Pantokar, Proxium, Zovanta, Pangastro, Pantex, Pantoprazole – Pharmex, Panum, Ultera, Lanza, Lansoprol, Lanzerol.

pharmachologic effect

A blocker of gastric secretion, an antiulcer agent, inhibits the secretion of hydrochloric acid in the stomach by specifically affecting the proton pump of parietal cells.

Indications for use

Treatment of mild reflux disease and its symptoms; long-term treatment and prevention of recurrence of reflux – esophagitis; prevention of gastric and duodenal ulcers caused by taking non-selective NSAIDs in high-risk patients taking NSAIDs for a long time. As part of combination therapy with certain antibiotics for the eradication of Helicobacter pylori   in patients with peptic ulcers caused by this microorganism, in order to reduce the number of recurrences of gastric and duodenal ulcers; peptic ulcer of the stomach and duodenum, reflux – moderate and severe esophagitis, Zollinger -Ellison syndrome . 

Method of administration and dosage

Adults and children over 12 years old.

Treating mild reflux disease and its symptoms.   The recommended dose is 20 mg of pantoprazole (active ingredient) per day. Symptoms disappear within 2–4 weeks of treatment. The associated esophagitis usually takes 4–8 weeks to heal. 

Long-term treatment and prevention of recurrence of reflux – esophagitis.   With long-term treatment, the maintenance dose is 20 mg of pantoprazole per day; in case of an expected exacerbation , it is possible to increase the dose to 40 mg per day. After elimination of the relapse, the dose can again be reduced to 20 mg of pantoprazole per day.    

Adults.

Prevention of gastric and duodenal ulcers caused by taking non-selective NSAIDs in patients at risk. The recommended dose is 20 mg of pantoprazole per day. 

For the treatment of reflux – esophagitis of moderate and severe degree:   40 mg of pantoprazole 1 time per day. In some cases, the dose can be doubled.  

For the long-term treatment of Zollinger -Ellison syndrome and other pathological hypersecretory conditions, the   initial daily dose is 80 mg of pantoprazole.  

Side effects

Rarely observed. Possible headache, diarrhea, nausea, epigastric pain, flatulence, skin rash and itching, dizziness, edema, depression, blurred vision.

Contraindications

Hypersensitivity to pantoprazole, renal dysfunction, minor gastro – intestinal disorders, pregnancy and lactation, children’s age.

Overdose

No data available.