Analogs

Celebrex, Rancelex, Phlogoxib – Health, Denebol, Denebol gel, Dynastat, Arkoksiya, Exinef, Sinmeton, Fletserin, Diamaks, Ortserin.

pharmachologic effect

It has anti-inflammatory and analgesic properties.

Indications for use

Symptomatic therapy of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

Dosage and administration

Osteoarthritis . The standard recommended daily intake for adults is 200 mg in 1–2 doses. 

Rheumatoid arthritis. The recommended dose is 100 mg 2 times a day.  

Ankylosing spondylitis . The recommended dose is 200 mg in 1–2 doses.  

Side effects

Abdominal pain, diarrhea, vomiting, dyspepsia, flatulence, dysphagia; dizziness, insomnia; anxiety, drowsiness.

Contraindications

Hypersensitivity, active peptic ulcer or bleeding in the digestive tract, inflammatory bowel disease, AD, acute rhinitis, nasal polyps, angioedema, urticaria and other allergic reactions in history, caused by the use of salicylates or NSAIDs, severe liver and kidney function, period pregnancy and lactation, age up to 18 years.

Overdose

Symptoms Angina pectoris, irritable bowel syndrome, nephrolithiasis, increased creatinine levels in the blood, benign prostatic hyperplasia, weight gain.