Analogs

Agvantar , Carniel , Heptral , Glutamic acid, Stimol , Almiba , Carnivit , Lekarnita .

pharmachologic effect

A natural substance required for energy metabolism. Facilitates the entry of long-chain fatty acids into the mitochondria of cells, thus providing a substrate for oxidation and energy generation.

Indications for use

Primary carnitine deficiency. Secondary carnitine deficiency. Cardiomyopathy . Intrahepatic cholestasis in adults, including patients with chronic hepatitis of various etiologies, and liver cirrhosis; intrahepatic cholestasis in pregnant women; depressive syndromes.

Method of administration and dosage

Doses and duration of treatment are set individually, depending on the age and nosological form of the disease. Steatel is taken orally 30 minutes before meals. For dosing, use a dosing syringe or measuring cup.

For adults, the   drug is prescribed at an initial dose of 1 g per day (10 ml), gradually increasing the dose depending on the patient’s condition and tolerance. The usual adult dose is 1-3 g (10-30 ml) per day, divided into 1-3 doses. The maximum daily dose for adults is 6 g (60 ml).       

Children   are prescribed starting from a dose of 50 mg / kg of body weight per day. The usual dose for children is 50–100 mg / kg per day.  

Side effects

With long-term use of L – carnitine, various minor gastrointestinal disorders have been reported, such as nausea and vomiting, flatulence, and diarrhea. Cases of mild myasthenia gravis have been described only with the use of L – carnitine in patients with uremia.

Sensitivity to the drug must be evaluated carefully for 1 – the first week of the drug and then increase the dose.

Contraindications

Hypersensitivity to the components of the drug, during pregnancy and lactation. Take with caution in diabetes mellitus, severe forms of renal dysfunction.

Overdose

The use of the drug in high doses can cause diarrhea.