Analogues

Zanidip , Nitresan , Lacipil .

pharmachologic effect

Has a hypotensive effect.

Indications for use

Essential hypertension of mild to moderate severity.

Dosage and administration

1 tablet (10 mg) 1 time per day at least 15 minutes before meals, preferably in the morning, without chewing, drinking plenty of water. Depending on the achieved therapeutic effect, the dose may be increased to 2 tablets (20 mg). The therapeutic dose is selected gradually, increasing the dose to 20 mg is carried out 2 weeks after the start of the drug.

Side effects

Rarely: peripheral edema, a feeling of “flushing” of blood to the face, palpitations, tachycardia, chest pain, marked decrease in blood pressure, angina pectoris, asthenia, fatigue, headache, dizziness; very rarely: gastrointestinal ‑disorders, reversible increase in the activity of “liver” enzymes, myocardial infarction, polyuria, skin rash, drowsiness, myalgia, gingival hyperplasia.

Contraindications

Hypersensitivity to lercanidipine , other derivatives of the dihydropyridine series or any component of the drug; chronic heart failure; unstable angina; obstruction of vessels emanating from the left ventricle of the heart; within 1 month after myocardial infarction; severe liver dysfunction; impaired renal function (creatinine clearance less than 12 ml / min); lactose intolerance, galactosemia , glucose / galactose malabsorption syndrome.

Pregnancy and lactation period; women of childbearing age not using reliable contraception. Age up to 18 years (efficacy and safety have not been studied). With caution: renal and / or liver failure, old age, sick sinus syndrome (without a pacemaker), coronary artery disease, left ventricular dysfunction.

Overdose

There are no reports of overdose.