Analogues

corinfar retard , Nifecard XL, Kordipin , Corinfar , Nicardia retard , Nifedipine ‑Darnitsa , Osmo ‑adalat , Farmadipin , Fenigidin , Fenigidin ‑Health, Felodip , Nemotan , Nimodipine , Nimotop , Kordipin XL, Kordipin retard , Corinfar uno 40, Nifedipine ‑Darnitsa , Nifecard , Nifedipine retard , Nimotopin .

pharmachologic effect

Expands the coronary and peripheral arterial vessels, reduces myocardial oxygen demand, lowers the total peripheral vascular resistance and blood pressure.

Indications for use

Angina pectoris, essential and symptomatic hypertension.

Dosage and administration

Inside, regardless of food intake, 10-30 mg 3-4 times a day.

To stop a hypertensive crisis, it is used sublingually at a dose of 10 mg in the form of a ‑pra for oral use (or after chewing the tablet), if necessary, after 20–30 minutes, the administration is repeated, sometimes increasing the dose to 20–30 mg, or the drug is administered intravenously. a dose of 5 mg for 4-8 hours; the maximum dose is 15–30 mg per day (for no more than 3 days).

For long-term treatment of hypertension and / or angina pectoris, retard ‑form should be used 1-2 times a day.

Side effects

Headache, drowsiness, dizziness, tachycardia, nausea, swelling of the lower extremities, flushing of the skin of the face and upper body. In these cases, the dose should be reduced.

Contraindications

The period of pregnancy and lactation, severe heart failure, sick sinus syndrome, severe arterial hypotension, porphyria, hypersensitivity to nifedipine or other dihydropyridine derivatives . With extreme caution should be used in patients with unstable angina and myocardial infarction.

Overdose

Manifested by arterial hypotension, bradycardia, heart failure, shock, metabolic acidosis and convulsions. Gastric lavage, activated charcoal, monitoring of hemodynamic parameters and symptomatic treatment are recommended.