Analogues

Amidaron, Myoritmil ‑Darnitsa, Rotaritmil, Amiocordin, Aritmil, CardiodaronHealth, Kordaron, Multak.

pharmachologic effect

Antiarrhythmic and antianginal agent.

Indications for use

Prevention of angina attacks, treatment and prevention of paroxysmal arrhythmias, as well as extrasystole.

Dosage and administration

For the prevention of angina attacks, as well as for the treatment and prevention of extrasystoles , adults are prescribed orally for the first 8-14 days, 0.2 g 2-3 times a day, then they switch to maintenance treatment – 0.2 g 1-2 times a day. day. The scheme and duration of treatment are set individually. The initial daily dose for children is 8-10 mg/kg body weight for 8-14 days; then proceed to treatment with a maintenance dose.

To eliminate acute arrhythmias , 5% glucose is administered slowly in / in 250 ml at a rate of 5 mg / kg; ‑if necessary, re-introduce after 24 hours.

Side effects

Possible deposition of lipofuscin in the corneal epithelium; photosensitivity; with prolonged use in rare cases, the development of hypothyroidism is possible, much less often – hyperthyroidism when used in high doses; bradycardia, slowing of AV ‑conduction, arterial hypotension, nausea, impaired liver function; in isolated cases – peripheral neuropathy, tremor, pulmonitis, alveolitis.

Contraindications

Sinus bradycardia, sick sinus syndrome, sinoatrial block, AV ‑block II and III degree; severe arterial hypotension, collapse, shock, hypothyroidism, hyperthyroidism, hypersensitivity to iodine, lactation period.

Overdose

No data.