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pharmachologic effect

It has a hypotensive effect on systolic and diastolic pressure, reduces the minute volume of blood circulation and stroke volume. With prolonged use, the heart rate decreases at rest and during periods of physical exertion. The drug also has a moderate antiarrhythmic effect.

Indications for use

Applied in adults for the treatment of such pathologies of ‑the cardiovascular system as: coronary artery disease; angina pectoris, rest angina pectoris, unstable angina pectoris; AG, hypertension; decrease in muscle tone at the mitral valve, hyperkinetic cardiac syndrome caused by functional disorders in the heart; neurocirculatory disorders with hypertensive complications; senile tremor, withdrawal tremor, essential tremor.

Also used for the treatment and prevention of myocardial infarction , including as maintenance therapy after acute conditions; arrhythmias of various etiologies; supraventricular and ventricular extrasystole, sinus tachycardia, paroxysmal atrial tachycardia, other types of arrhythmias; atrial flutter.

In complex treatment: thyrotoxicosis , migraine prevention, hypertrophic obstructive cardiomyopathy.

Dosage and administration

Tablets are recommended to be taken before meals. The tablet is swallowed without chewing, drinking plenty of water. The dose of the drug is selected individually, the initial therapeutic dose for angina pectoris is 50 mg once, in the absence or insufficiency of the effect, the dose is increased. The maximum daily dose is 200 mg (in case of impaired renal function and in elderly patients, the maximum dose is less).

The maintenance dose is usually 25 mg once daily but may be increased by the physician.

Side effects

Most side effects are mild and usually disappear after 2-3 weeks of regular use of the drug. If the therapeutic dose is exceeded, the frequency and severity of side effects increase dramatically.

There may be weakness, dizziness, fatigue, decreased concentration, memory impairment.

Sleep disturbance, anxiety, depression, hallucinations, convulsions, tremors. Decreased activity of the external secretion glands, impaired visual function.


Individual hypersensitivity to the components of the drug; sinus bradycardia; cardiogenic shock; atrioventricular block II and III stage; arterial hypotension; acute and chronic heart failure; sinoauricular blockade; bronchial asthma; violation of the acid- ‑base balance in the body in the direction of acidosis.

Use with caution in patients suffering from: diabetes mellitus, chronic obstructive pulmonary and bronchial diseases, impaired liver and kidney function.

In childhood and old age, as well as in patients with depression, psoriasis, myasthenia gravis, atenolol is prescribed with caution.


Symptoms . In case of overdose, patients experience bradycardia, atrioventricular blockade, respiratory failure, hypotension, shock, collapse, bronchospasm, hypoglycemia.

Treatment . Shown gastric lavage, intake of adsorbents.

If necessary, sympathomimetic drugs, cardiac glycosides, diuretics, selective B- ‑agonists are administered.

With the development of hypoglycemia, intravenous drip of glucose is indicated.

In severe cases, dialysis is performed.

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