Lidocaine hydrochloride, Lidocaine – Darnitsa, Lidocaine – Health, Cathejel with lidocaine, Emla , Emla plaster, Luan gel, Instillagel , Naropin Benoxi , Versatis .

pharmachologic effect

Local anesthetic agent used for all kinds of local anesthesia: terminal, infiltration, conduction.

Indications for use

Local anesthesia in surgery, ophthalmology, dentistry, otolaryngology; blockade of peripheral nerves and nerve plexuses for various pain syndromes.

Method of administration and dosage

Before using the drug, it is necessary to conduct a skin test for increased individual sensitivity to the drug, as evidenced by edema and redness of the injection site.

For local anesthesia, it is   used by injection (s / c, i / m) and topically on the mucous membranes. Intravascular administration should be avoided. 

For conduction anesthesia (including pain management brachial plexus and the sacral)   usual adult dosage is 5-10 ml p – pa (100-200 mg).  

For anesthesia fingers, nose, ears   administered 2-3 ml p – pa (40-60 mg). The maximum dose of p – pa adult when used for conduction anesthesia – 10 ml (200 mg).     

For anesthesia in ophthalmology   2 drops p – pa instilled into the conjunctival sac 2-3 times with an interval of just 30-60 seconds before testing or surgery.

Side effects

Dizziness, headache, weakness, motor restlessness, euphoria, nystagmus, loss of consciousness, drowsiness, sleep disturbances, visual and auditory disturbances, tremor, trismus, convulsions, paresthesias, respiratory muscle paralysis, motor blockade, sensory disturbances, respiratory paralysis, numbness of the tongue and lips, allergic reactions.


Individual hypersensitivity to the components of the drug, as well as to other amide local anesthetic drugs; specifying a history of epileptiform seizures associated with the administration of lidocaine hydrochloride, AV – blockade of II and III degree, sick sinus syndrome, WPW – syndrome, Adams syndrome – Stokes, severe heart failure (II-III degree), marked hypotension, bradycardia, cardiogenic shock; complete transverse heart block; myasthenia gravis; hypovolemia; porphyria; severe renal and / or hepatic impairment; retrobulbar administration to patients with glaucoma; During pregnancy and breastfeeding; age up to 12 years.   


The main symptoms   are associated with inhibition of the central nervous system and cardio – vascular system: general weakness, dizziness, disorientation, tonic – clonic seizures, coma, tremors, blurred vision, the AV – blockade, asphyxia, nausea, vomiting, euphoria, agitation, fatigue, sleep apnea , bradycardia, lowering blood pressure, collapse.

Treatment.   Discontinuation of drug administration, oxygen therapy, vasoconstrictors (norepinephrine, phenylephrine ), anticonvulsants, anticholinergics . The patient must be in a horizontal position; it is necessary to provide access to fresh air, oxygen supply and / or artificial respiration.

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