Nalgesin forte, Naproff, Promax, Ketonal, Mazhezik – Sanovel, Zotek, Dexalgin, Dexalgin injection, Depiofen, Mefenamic acid – Darnitsa, Naproxen.

pharmachologic effect

It has analgesic, anti-inflammatory and antipyretic effects.

Indications for use

Headache and toothache, migraine, menstrual pain; pain in muscles, joints and pain in the spine, pain in muscles and joints with colds and flu, rheumatoid diseases.

Dosage and administration

Toothache, headache and disorders of the musculoskeletal – musculoskeletal system .

The recommended dose is 2 tablets (550 mg) 2 times a day, not more than 4 tablets (1100 mg) per day.  

Migraine . The recommended dose is 3 tablets (825 mg) at the first sign of an approaching attack. If necessary, during the day you can take 1 tablet (275 mg) or 2 tablets (550 mg), but not earlier than half an hour after taking the initial dose. Do not exceed the total dose of 5 tablets (1375 mg) per day.    

Menstrual pain . The initial recommended dose is 2 tablets (550 mg). Then, if necessary, take 1 tablet (275 mg) every 6-8 hours.   

In the case of an acute attack of gout, the initial dose is 825 mg (1.5 tablets), then 275 mg (half a tablet) is taken every 8 hours until the attacks stop and until the daily dose exceeds 1375 mg.     

The initial dose for rheumatic diseases ranges from 550 to 1100 mg and is divided into receptions in the morning and evening. Doses in the morning and evening should not be the same; they should be adjusted according to the prevailing symptoms. 

Side effects

Eosinophilia, granulocytopenia, leukopenia, thrombocytopenia, aplastic anemia, hemolytic anemia; hypersensitivity reactions, anaphylactic reactions, headache, vertigo, dizziness, drowsiness, depression, sleep disturbance, inability to concentrate, insomnia, weakness, aseptic meningitis, cognitive impairment; convulsions, abnormal dreams.


Hypersensitivity to naproxen sodium, to salicylates and other NSAIDs, manifested in the form of AD, urticaria and nasal polyps. An acute period or relapse of a stomach ulcer or duodenal ulcer, hemorrhage in the digestive tract. Severe impairment of liver and kidney function. Heart failure. During pregnancy and breastfeeding. Age to 16 years.


Symptoms . Abdominal pain, nausea, vomiting, dizziness, tinnitus, irritability, bloody vomiting, melena, impaired consciousness, respiratory distress, convulsions and renal failure.

Treatment . Gastric lavage, administration of activated carbon, antacids, H2 – receptor inhibitors, proton pump inhibitors, misoprostol, etc. 

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