Analogs

Naproff, Nimesil, Ibuprofen, Diclofenac sodium, Ketorolac.

pharmachologic effect

It has anti-inflammatory, analgesic, antipyretic and anti-edema effects.

Indications for use

Rheumatism, rheumatoid arthritis, juvenile arthritis, ankylosing spondylitis, osteoarthritis, gout, pain syndrome of various origins, including post-traumatic and postoperative pain syndrome, headache, toothache, dysmenorrhea, pharyngitis, tonsillitis, otitis media, febrile syndrome and infectious diseases, childbirth. 

Local treatment: pain in muscles and joints; with degenerative diseases of the joints.

Method of administration and dosage

Pills. Swallow whole, drink some liquid, take with meals. 

Acute gout attack : first dose – 825 mg; then – 275 mg every 8 hours.     

Algodismenorrhea: first dose – 500 mg, then – 275 mg every 6-8 hours for 3-4 days.       

Migraine: 500 mg.   

Rectal suppositories. Usually used at night for 1 candle 0.5 g.   

Suspension. It is the preferred dosage form for children. 

Side effects

Irritation, rash, skin rash, eosinophilic pneumonia; thrombocytopenia, granulocytopenia, aplastic anemia, hemolytic anemia, nausea, vomiting, diarrhea, drowsiness, headache, erythema, urticaria, pruritus, angioedema, tinnitus, hearing loss, dizziness, weakness, delayed reaction rate, erosive – ulcerative Gastrointestinal tract, bleeding and perforation of the gastrointestinal tract, impaired renal or liver function.

Contraindications

Age up to 1 year.

Hypersensitivity to the components of the drug, pregnancy (III trimester), lactation period, erosive – ulcerative lesions of the gastrointestinal tract in the acute phase, inhibition of bone marrow hematopoiesis, hepatic and / or renal failure.

Overdose

Symptoms Heartburn, indigestion, nausea, vomiting, drowsiness. 

Treatment. Rinse the stomach, take activated charcoal – 0.5 g / kg.