Analogs

Armadin, Armadin injection, Biotropil, Glycised, Keltikan, Cortexin, Lucetam, Memozam, Neuro – norms, Noozam, Nootropil, Olatropil, Omaron, Piracetam – Darnitsa, Piracetam – Health, Pramistar, Thiocetam, Fezam, Eurizatropil – health , Mexiprim, Nucleo Ts.M.F. forte, Dr. Schussler’s salt No. 5 potassium, Phosphoricum, Cerebrum compositum, Cytoflavin, Enerion. 

pharmachologic effect

A nootropic agent that has a positive effect on metabolic processes and blood circulation in the brain, improves cognitive processes, as well as mental performance. Inhibits platelet aggregation and restores the elasticity of the erythrocyte membrane, reduces erythrocyte adhesion. It has a protective and restorative effect in case of dysfunction of the brain due to hypoxia and intoxication.

Indications for use

Cerebral circulation disorders: cerebrovascular atherosclerosis, accompanied by ischemic stroke; in the period of rehabilitation after a hemorrhagic stroke, traumatic – brain injury; memory impairment, thinking function, concentration of attention; vascular dementia; mood disorders (with depression and irritability); encephalopathy of various origins; labyrinthopathies of various origins; Meniere’s syndrome; in the complex treatment of sensorineural hearing loss.  

Method of administration and dosage

Pills . Used internally. The daily dose for an adult is 30–160 mg / kg, the frequency of administration is 2–4 times a day, during meals or on an empty stomach; the tablets should be taken with a liquid (water, juice).    

In the symptomatic treatment of chronic psychoorganic syndrome , depending on the severity of symptoms, 4.8 g is prescribed per day (12 tablets – 400 mg, or 6 tablets – 800 mg, or 4 tablets – 1200 mg) for the first few weeks, followed by a decrease in the maintenance dose in within 1.2-2.4 g per day (3-6 tablets – 400 mg, or 1.5-3 tablets – 800 mg, or 1-2 tablets – 1200 mg).                

With the consequences of a stroke (chronic stage), 4.8 g per day is prescribed . In case of difficulties of perception for persons with brain injuries, the initial dose is 9–12 g per day, the maintenance dose is 2.4 g per day. The duration of treatment is at least 3 weeks.       

Children over the age of 7 years are prescribed 3.3 g per day to correct the reduced learning ability . Treatment is long-term, throughout the school year.   

With cortical myoclonus, treatment begins with 7.2 g per day, every 3-4 days the dose is increased by 4.8 g per day until a maximum dose of 24 g per day is reached . The therapy is continued throughout the entire period of the illness. Every 6 months, the dose is gradually reduced or discontinued. In order to prevent an attack, the dose is reduced gradually, by 1.2 g every 2 days. In the absence of effect or in the case of an insignificant therapeutic effect, treatment is discontinued.      

Side effects

Nausea, vomiting, diarrhea, abdominal and stomach pain. Allergic reactions.

Contraindications

Diseases of the kidneys or liver, I trimester of pregnancy and lactation, age up to 5 years, parkinsonism, hypersensitivity to the components of the drug.

Overdose

When taking 75 g of Piracetam inside, such dyspeptic phenomena as bloody diarrhea and abdominal pain were noted. There were no other symptoms in case of an overdose of the drug. 

Treatment. Symptomatic. Immediately after a significant oral overdose, gastric lavage or induce vomiting should be performed. There is no specific antidote. The effectiveness of hemodialysis is 50-60 %.